[セミナー］第39回IPB セミナー

[セミナー］第39回IPB セミナーを下記の通り開催します。
日時：2023年6月26日（月）16:00-17:00
場所：生命創生探究センター 山手３号館２階大会議室　hybrid開催
講演者： 神野 圭太 氏(Academia Sinica)
タイトル：Efficient information usage by cells – and cell biologists
※参加希望の方はご登録下さい↓ (本セミナーは日本語で実施されます)
https://forms.gle/iky2ZFVndS8vEUg28

Abstract:
Organisms acquire and use sensory information to guide their behaviors. Likewise, scientists acquire and use the information contained in experimental data to better understand systems of interest. In both cases, the amounts of information available are usually limited, so using it efficiently is critical. In this seminar, I will discuss two aspects of efficient information usage. First, I explore information usage by cells, describing how we have discovered that motile Escherichia coli cells (arguably the simplest model of biological behavior) acquire very little information but use it highly efficiently. Second, I examine information usage by scientists, elaborating on how faced with noisy fluorescence data from single E. coli cells, we developed a method to extract relevant signals from raw data with theoretically maximal efficiency. Finally, I examine similarities between these two processes.

References:
1. Kamino, K., Keegstra, J. M., Long, J., Emonet, T., & Shimizu, T. S. (2020). Adaptive tuning of cell sensory diversity without changes in gene expression. Science Advances, 6(46), eabc1087.
2. Mattingly*, H. H., Kamino*, K., Machta, B. B., & Emonet, T. (2021). Escherichia coli chemotaxis is information limited. Nature Physics, 17(12), 1426-1431. (*Equal contribution)
3. Kamino*, K., Kadakia, N., Avgidis, F., Liu, Z. X., Aoki, K., Shimizu, T. S., & Emonet*, T. (2023). Optimal inference of molecular interaction dynamics in FRET microscopy. PNAS, 120(15), e2211807120. (*Corresponding authors)